Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925896 | 0.80 | NPC1 (0.40) | SMN1; SMN2CYP1A2CYP2D6MAPK1ALDH1A1 | |
| SCHEMBL10922582 | 0.80 | NPC1 (0.40) | SMN1; SMN2CYP1A2CYP2D6MAPK1ALDH1A1 | |
| SCHEMBL10925047 | 0.79 | NPC1 (0.42) | SMN1; SMN2ALOX15CYP1A2CYP2D6HPGD | |
| SCHEMBL11376480 | 0.79 | UBE2T (0.41) | SMN1; SMN2ALOX15HTTCYP1A2CYP2D6 | |
| SCHEMBL19385848 | 0.76 | FBP1 (0.43) | SMN1; SMN2ALOX15CYP1A2CYP2D6HPGD | |
| SCHEMBL19385849 | 0.76 | FBP1 (0.43) | SMN1; SMN2ALOX15CYP1A2CYP2D6HPGD | |
| SCHEMBL9186126 | 0.76 | UBE2T (0.36) | SMN1; SMN2ALOX15HTTCYP1A2CYP2D6 | |
| SCHEMBL5848920 | 0.74 | CYP2A6 (0.31) | — | |
| SCHEMBL6799340 | 0.73 | CYP1A2 (0.65) | SMN1; SMN2HTTCYP1A2CYP2D6HPGD | |
| SCHEMBL10926335 | 0.73 | MAPT (0.52) | SMN1; SMN2ALOX15CYP1A2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710045-B2 | FOR CONTROLLING ANIMAL PESTS, IN PARTICULAR INSECTS, ARACHNIDS AND NEMATODES | BAYER CROPSCIENCE AG (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20030187259-A1 | Heterocylic fluoroalkenyl thioethers and the use thereof as pesticides (IV) | BAYER CROPSCIENCE AG (DE) | 2003-10-02 | — | — | US | disclosed |
| EP-1311497-A1 | HETEROCYCLIC FLUOROALKENYL THIOETHERS AND THE USE THEREOF AS PESTICIDES (IV) | Bayer CropScience AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002006259-A1 | HETEROCYCLIC FLUOROALKENYL THIOETHERS AND THE USE THEREOF AS PESTICIDES (IV) | BAYER CROPSCIENCE AG (DE) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187259-A1 | Heterocylic fluoroalkenyl thioethers and the use thereof as pesticides (IV) | DDT, CYP4F2, CYP4F3 | SMN1; SMN2 3173/4885ALOX15 335/4885HTT 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.