Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799548 | 0.88 | CFTR (0.50) | CFTRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6805059 | 0.86 | PSEN1 (0.52) | LSSPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23354519 | 0.83 | CFTR (0.63) | CFTRKDM4ESLC6A4SLC6A3BACE1 | |
| SCHEMBL6808895 | 0.82 | CFTR (0.47) | CFTRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6803026 | 0.81 | CFTR (0.51) | CFTRKDM4ESLC6A4SLC6A3BACE1 | |
| SCHEMBL2138612 | 0.79 | CFTR (0.55) | CFTRKDM4ESLC6A4SLC6A3BACE1 | |
| SCHEMBL6698582 | 0.79 | CFTR (0.55) | CFTRKDM4ESLC6A4SLC6A3MTTP | |
| SCHEMBL23354287 | 0.79 | SLC6A3 (0.56) | CFTRKDM4ESLC6A4SLC6A3BACE1 | |
| SCHEMBL6701426 | 0.78 | KDM4E (0.58) | CFTRKDM4ESLC6A4SLC6A3BACE1 | |
| SCHEMBL23354056 | 0.77 | CFTR (0.52) | CFTRKDM4ESLC6A4SLC6A3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | LSS 1798/4885CFTR 1213/4885PSEN1 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.