SCHEMBL6804252

SCHEMBL6804252

O=C1/C(=C/c2cc(O)c(O)c(O)c2)Oc2c1ccc(O)c2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.81
TYR P14679 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6610772 1.00 APP (0.81) APPTYR
SCHEMBL6614096 0.90 APP (0.74) APPTYR
SCHEMBL6802883 0.90 APP (0.74) APPTYR
SCHEMBL6808382 0.90 APP (1.00) APP
SCHEMBL6611437 0.90 APP (1.00) APP
SCHEMBL30931489 0.90 APP (1.00) APP
SCHEMBL6614747 0.88 APP (0.68) APP
SCHEMBL6809157 0.88 APP (0.68) APP
SCHEMBL6808949 0.87 APP (0.71) APPTYR
SCHEMBL6615095 0.87 APP (0.71) APPTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040132807-A1 Aurones as telomerase inhibitors PHARMACIA ITALIA SPA (IT) 2004-07-08 US claimed
US-20040132807-A1 Aurones as telomerase inhibitors PHARMACIA ITALIA SPA (IT) 2004-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040132807-A1 Aurones as telomerase inhibitors TERT, TERF2, TERF2IP APP 3533/4885TYR 2826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.