Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.60 |
| ▸ | CTSV | O60911 | 6/20 | 0.60 |
| ▸ | CTSL | P07711 | 5/20 | 0.60 |
| ▸ | CTSK | P43235 | 14/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807943 | 0.93 | CTSS (0.57) | CTSSCTSVCTSLCTSK | |
| SCHEMBL6797981 | 0.92 | CTSS (0.69) | CTSSCTSVCTSLCTSKCTSB | |
| SCHEMBL4452629 | 0.89 | CTSK (0.55) | CTSSCTSVCTSLCTSK | |
| SCHEMBL6805474 | 0.89 | CTSS (0.65) | CTSSCTSVCTSLCTSK | |
| SCHEMBL5258667 | 0.89 | CTSK (0.56) | CTSSCTSVCTSLCTSK | |
| SCHEMBL4449564 | 0.88 | CTSK (0.59) | CTSSCTSVCTSLCTSK | |
| SCHEMBL4446428 | 0.87 | CTSK (0.63) | CTSSCTSVCTSLCTSK | |
| SCHEMBL6804162 | 0.87 | CTSS (0.60) | CTSSCTSVCTSLCTSK | |
| SCHEMBL6798717 | 0.86 | CTSK (0.57) | CTSSCTSVCTSLCTSK | |
| SCHEMBL5256435 | 0.86 | CTSK (0.75) | CTSSCTSVCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | GRUNENTHAL GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | CPN1, CTRL, CPA1 | CTSS 39/4885CTSV 27/4885CTSL 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.