Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804717 | 1.00 | TYR (0.71) | TYRAPP | |
| SCHEMBL6610022 | 0.89 | TYR (0.64) | TYRAPP | |
| SCHEMBL6813042 | 0.89 | TYR (0.64) | TYRAPP | |
| SCHEMBL6809481 | 0.87 | TYR (0.62) | TYRAPP | |
| SCHEMBL6809484 | 0.87 | TYR (0.62) | TYRAPP | |
| SCHEMBL6611665 | 0.84 | TYR (0.82) | TYRAPP | |
| SCHEMBL6809468 | 0.84 | TYR (0.82) | TYRAPP | |
| SCHEMBL6809219 | 0.84 | TYR (0.58) | TYRAPP | |
| SCHEMBL6614113 | 0.84 | TYR (0.58) | TYRAPP | |
| SCHEMBL6807807 | 0.84 | APP (0.72) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132807-A1 | Aurones as telomerase inhibitors | PHARMACIA ITALIA SPA (IT) | 2004-07-08 | — | — | US | claimed |
| US-20040132807-A1 | Aurones as telomerase inhibitors | PHARMACIA ITALIA SPA (IT) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132807-A1 | Aurones as telomerase inhibitors | TERT, TERF2, TERF2IP | TYR 2826/4885APP 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.