⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720252 | 0.87 | — | — | |
| SCHEMBL3880842 | 0.77 | — | — | |
| SCHEMBL8997496 | 0.72 | — | — | |
| SCHEMBL1796278 | 0.69 | — | — | |
| SCHEMBL4261229 | 0.67 | — | — | |
| SCHEMBL9473030 | 0.65 | — | — | |
| SCHEMBL5812637 | 0.64 | — | — | |
| SCHEMBL8613697 | 0.64 | — | — | |
| SCHEMBL4937018 | 0.64 | — | — | |
| SCHEMBL147886 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288240-A1 | NOVEL PHOSPHAZENE-SUPPORTED CATALYST, NOVEL COMPOUND THEREOF AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-1775301-B1 | NOVEL SUPPORTED PHOSPHAZENE CATALYSTS, NOVEL COMPOUNDS FOR THE CATALYSTS, AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-20080318767-A1 | Novel Phosphazene-Supported Catalyst, Novel Compound Thereof and Use Thereof | MITSUI CHEMICALS, INC. (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1775301-A1 | NOVEL SUPPORTED PHOSPHAZENE CATALYSTS, NOVEL COMPOUNDS FOR THE CATALYSTS, AND USE THEREOF | Mitsui Chemicals Polyurethanes, Inc. (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-6617456-B1 | Aminoalkoxy- or hydroxyalkoxy- camptothecin compound that can be bound to a polysaccharide having carboxyl groups via an amino acid or a peptide group; antitumor agents | TANABE SEIYAKU CO., LTD. (JP) | 2003-09-09 | — | — | US | disclosed |
| US-6512118-B1 | Pharmaceutically acceptable salt thereof show excellent antitumor activities against various tumors, especially they show excellent therapeutic effects on solid tumors such as pulmonary cancer, uterine cancer, ovarian cancer, breast | TANABE SEIYAKU CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-0781781-B1 | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-5892043-A | MIXTURE WITH POLYSACCHARIDE AND PEPTIDE; ANTITUMOR AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0781781-A2 | Camptothecin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| US-4978782-A | WITHOUT AMINO-NITROGEN | VANDERBILT UNIVERSITY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4943657-A | Unsymmetrical organic disulfide compounds useful as antiradiation agents | VANDERBILT UNIVERSITY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4883890-A | CONTAIN SULFINATE GROUP | VANDERBILT UNIVERSITY (US) | 1989-11-28 | — | — | US | disclosed |