Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.53 |
| ▸ | CTSV | O60911 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805371 | 0.97 | CTSS (0.54) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6802332 | 0.94 | CTSS (0.51) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6808187 | 0.94 | CTSS (0.51) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6797583 | 0.94 | CTSS (0.51) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6798994 | 0.94 | CTSS (0.51) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6803432 | 0.94 | CTSS (0.51) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6808737 | 0.94 | CTSS (0.52) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6799215 | 0.91 | CTSS (0.49) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6798408 | 0.90 | CTSS (0.65) | CTSSCTSVCTSLCTSKROCK2 | |
| SCHEMBL6798333 | 0.90 | CTSK (0.60) | CTSSCTSVCTSLCTSKFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | GRUNENTHAL GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | CPN1, CTRL, CPA1 | CTSS 39/4885CTSV 27/4885CTSL 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.