SCHEMBL680504

SCHEMBL680504

CC(=CCCc1ccc(C)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 1/20 0.46
FFAR1 O14842 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CTBP2 P56545 1/20 0.42
PPARG P37231 1/20 0.40
GRIK1 P39086 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 1/20 0.39
PLAAT3 P53816 1/20 0.39
PLAAT5 Q96KN8 1/20 0.39
PLAAT2 Q9NWW9 1/20 0.39
PLAAT4 Q9UL19 1/20 0.39
SRD5A2 P31213 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SLC5A1 P13866 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12003203 1.00 GPR52 (0.46) GPR52FFAR1TDP1L3MBTL1CTBP2
SCHEMBL970820 0.86 KDM4E (0.47) L3MBTL1CTBP2GRIK1TAAR1LMNA
SCHEMBL440430 0.86 THRB (0.46) L3MBTL1PPARGGRIK1NPC1RAB9A
SCHEMBL970817 0.86 KDM4E (0.47) L3MBTL1CTBP2GRIK1TAAR1LMNA
SCHEMBL1920798 0.86 THRB (0.46) L3MBTL1PPARGGRIK1NPC1RAB9A
SCHEMBL1919934 0.86 GPR52 (0.50) GPR52FFAR1PPARGGRIK1TAAR1
SCHEMBL441351 0.86 GPR52 (0.50) GPR52FFAR1PPARGGRIK1TAAR1
SCHEMBL197322 0.85 GRIK1 (0.53) GPR52GRIK1SMN1; SMN2NPC1RAB9A
SCHEMBL197321 0.85 GRIK1 (0.53) GPR52GRIK1SMN1; SMN2NPC1RAB9A
SCHEMBL1921003 0.84 DAO (0.44) FFAR1CTBP2CYP1A2TAAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-2341102-B1 Thermoplastic resin composition revealing improved impact strength and melt flow property CHEIL IND INC (KR) 2015-12-02 EP claimed
US-8907013-B2 Polycarbonate resin composition and molded product using the same CHEIL INDUSTRIES INC. (KR) 2014-12-09 US claimed
US-8835558-B2 Polylactic acid/polycarbonate resin composition and molded product made using the same CHEIL INDUSTRIES INC. (KR) 2014-09-16 US claimed
EP-2199342-B1 Polylactic acid/polycarbonate resin composition and molded product made using the same CHEIL IND INC (KR) 2014-07-30 EP claimed
US-8735490-B2 Thermoplastic resin composition having improved impact strength and melt flow properties CHEIL INDUSTRIES INC. (KR) 2014-05-27 US claimed
EP-2268709-B1 SCRATCH RESISTANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2013-10-02 EP claimed
EP-2204412-B1 Polycarbonate resin composition with improved scratch resistance and melt flow index CHEIL IND INC (KR) 2012-08-29 EP claimed
US-20110281995-A1 Polycarbonate Resin Composition and Molded Product Using the Same CHEIL INDUSTRIES INC. (KR) 2011-11-17 US claimed
EP-2341102-A1 Thermoplastic resin composition revealing improved impact strength and melt flow property Cheil Industries Inc. (KR) 2011-07-06 EP claimed
US-20110160377-A1 Thermoplastic Resin Composition Having Improved Impact Strength and Melt Flow Properties CHEIL INDUSTRIES INC. (KR) 2011-06-30 US claimed
US-20100160559-A1 Polylactic Acid/Polycarbonate Resin Composition and Molded Product Made Using the Same CHEIL INDUSTRIES INC. (KR) 2010-06-24 US claimed
EP-2199342-A2 Polylactic acid/polycarbonate resin composition and molded product made using the same Cheil Industries Inc. (KR) 2010-06-23 EP claimed
EP-1080382-B1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS ALCON INC (CH) 2009-07-08 EP claimed
US-11649401-B2 Quantum dot-containing material, method of preparing the same, and optical member and apparatus including the quantum dot-containing material SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-20230006135-A1 COMPOSITION FOR ENCAPSULATING ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE DISPLAY COMPRISING ORGANIC LAYER FORMED USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-01-05 US disclosed
EP-2199342-A2 Polylactic acid/polycarbonate resin composition and molded product made using the same Cheil Industries Inc. (KR) 2010-06-23 EP disclosed
EP-2184321-A2 Thermoplastic resin composition and molded product made using the same Cheil Industries Inc. (KR) 2010-05-12 EP disclosed
US-20100113697-A1 Thermoplastic Resin Composition and Molded Product Made Using the Same CHEIL INDUSTRIES INC. 2010-05-06 US disclosed