Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783973 | 0.94 | TDP1 (0.58) | TDP1L3MBTL1RAB9ASMN1; SMN2HTT | |
| SCHEMBL6804365 | 0.83 | KDM4E (0.61) | TDP1L3MBTL1RAB9ASMN1; SMN2HTT | |
| SCHEMBL6799807 | 0.78 | STS (0.54) | TDP1L3MBTL1 | |
| SCHEMBL14989351 | 0.77 | KMT2A (0.51) | TDP1L3MBTL1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1888642 | 0.75 | ALDH1A1 (0.59) | TDP1L3MBTL1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11513125 | 0.74 | KMT2A (0.49) | TDP1L3MBTL1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11320493 | 0.74 | KMT2A (0.66) | RAB9AHTTKMT2ACES2NPC1 | |
| SCHEMBL8173955 | 0.74 | TDP1 (1.00) | TDP1L3MBTL1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2114814 | 0.73 | ESR1 (0.66) | RAB9ASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL729118 | 0.73 | CES2 (0.54) | TDP1L3MBTL1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |