Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SOD1 | P00441 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219762 | 0.98 | GAA (0.50) | GAAGSK3AGSK3BKDM4ECHRM2 | |
| SCHEMBL3022499 | 0.76 | GSK3A (0.60) | GAAGSK3AGSK3BKDM4ETSHR | |
| SCHEMBL3013325 | 0.76 | GAA (0.59) | GAAGSK3AGSK3BKDM4EADRB1 | |
| SCHEMBL6592278 | 0.76 | GAA (0.43) | GAAGSK3AGSK3BKDM4ESMN1; SMN2 | |
| SCHEMBL11615640 | 0.71 | GSK3A (0.52) | GSK3AGSK3BKDM4ECHRM2CHRM4 | |
| SCHEMBL11608487 | 0.71 | TP53 (0.53) | GAAGSK3AGSK3BKDM4EADRB1 | |
| SCHEMBL11612676 | 0.69 | KDM4E (0.39) | GAAGSK3AGSK3BKDM4ECHRM2 | |
| SCHEMBL38660365 | 0.67 | SMN1; SMN2 (0.37) | KDM4ECHRM2CHRM4ADRB1CHRM1 | |
| 1,3,5-Trichlorobenzene SCHEMBL28192425 | 0.66 | TSHR (0.89) | CHRM2CHRM4ADRB1CHRM1CHRM3 | |
| SCHEMBL1746213 | 0.65 | KDM4E (0.40) | KDM4ECHRM2CHRM4ADRB1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673825-B2 | ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-20030013745-A1 | Urazole compounds useful as anti-inflammatory agents | CEREP SA (FR) | 2003-01-16 | — | — | US | disclosed |
| US-4162315-A | 1,2-(TETRAMETHYLENE)-4-(3,5-DICHLOROPHENYL)URAZOLES | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1979-07-24 | — | — | US | disclosed |
| US-4049820-A | Substituted urazole and thiourazole compounds as agricultural fungicidal agents | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013745-A1 | Urazole compounds useful as anti-inflammatory agents | TPMT, IL4, IL5 | GAA 3329/4885GSK3A 4464/4885GSK3B 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.