Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 4/20 | 0.93 |
| ▸ | AURKA | O14965 | 3/20 | 0.93 |
| ▸ | KDR | P35968 | 2/20 | 0.93 |
| ▸ | PARP1 | P09874 | 16/20 | 0.68 |
| ▸ | DHODH | Q02127 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805210 | 0.97 | AURKB (1.00) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6806882 | 0.89 | AURKA (0.78) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL3585484 | 0.88 | PARP1 (0.75) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6590662 | 0.88 | AURKB (0.72) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6810125 | 0.88 | AURKA (0.74) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6802562 | 0.87 | AURKA (0.84) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6806441 | 0.86 | AURKB (0.70) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6805911 | 0.86 | AURKA (0.74) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6804561 | 0.86 | AURKB (0.93) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6809970 | 0.85 | AURKA (0.73) | AURKBAURKAKDRPARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |