Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488395 | 0.85 | RECQL (0.55) | MAPTRAB9ASMN1; SMN2RECQLMEN1 | |
| SCHEMBL30665825 | 0.85 | RECQL (0.55) | MAPTRAB9ASMN1; SMN2RECQLMEN1 | |
| SCHEMBL3526801 | 0.81 | KMT2A (0.56) | MAPTRAB9ASMN1; SMN2RECQLMEN1 | |
| SCHEMBL6798465 | 0.78 | CA9 (0.78) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11509602 | 0.77 | KMT2A (0.65) | MAPTRAB9ASMN1; SMN2RECQLMEN1 | |
| SCHEMBL7375875 | 0.76 | HTT (0.60) | MAPTRAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL4667754 | 0.76 | STS (0.67) | CA1CA2CA9CA12LMNA | |
| SCHEMBL28584082 | 0.73 | WDR5 (0.56) | MAPTRAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL2336518 | 0.72 | RECQL (0.68) | MAPTSMN1; SMN2LMNARECQLMEN1 | |
| SCHEMBL4666136 | 0.72 | CA1 (0.52) | CA1CA2CA9CA12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |