Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806673 | 0.82 | KDM4E (0.42) | ALDH1A1KMT2AKDM4ETDP1SRC | |
| SCHEMBL21269629 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ETDP1PTGS2SRC | |
| SCHEMBL21268965 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ETDP1SRCPOLB | |
| SCHEMBL21269842 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ETDP1SRCPOLB | |
| SCHEMBL24269954 | 0.79 | GRM1 (0.47) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL6841189 | 0.78 | MAPT (0.39) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL26685846 | 0.78 | GRM1 (0.46) | ALDH1A1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL6839567 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL21269564 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL21268888 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759548-B2 | PESTICIDES AND HERBICIDES. PHENYL-SUBSTITUTED CYCLIC KETOENOLS, A PLURALITY OF PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | FISCHER REINER (DE) | 2003-07-31 | — | — | US | disclosed |
| EP-0835243-B1 | DIALKYL PHENYL HALIDE-SUBSTITUTED KETO-ENOLS FOR USE AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6469196-B2 | PESTICIDES AND WEEDKILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | FISCHER REINER (DE) | 2002-02-21 | — | — | US | disclosed |
| US-6251830-B1 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-5994274-A | Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0835243-A1 | DIALKYL PHENYL HALIDE-SUBSTITUTED KETO-ENOLS FOR USE AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997002243-A1 | DIALKYL PHENYL HALIDE-SUBSTITUTED KETO-ENOLS FOR USE AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | DDT, CYP8B1, CYP1A1 | ALDH1A1 566/4885CYP1A2 14/4885MEN1 4412/4885 |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | DDT, CYP2E1, CYP8B1 | ALDH1A1 549/4885CYP1A2 16/4885MEN1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.