SCHEMBL6806812

SCHEMBL6806812

O=C(c1ccccc1)N(OCO)[C@H]1CC[C@@H](c2ccc(O)cc2O)CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.47
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM3 P20309 1/20 0.35
MRGPRX4 Q96LA9 2/20 0.35
CHRNA7 P36544 1/20 0.35
OPRM1 P35372 5/20 0.34
OPRD1 P41143 5/20 0.34
PDK1 Q15118 1/20 0.33
ESRRG P62508 2/20 0.33
OPRK1 P41145 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6806811 1.00 TYR (0.47) TYRMEN1USP2GAAKMT2A
SCHEMBL6799615 0.81 TYR (0.46) TYRMEN1USP2GAAKMT2A
SCHEMBL6802537 0.81 TYR (0.46) TYRMEN1USP2GAAKMT2A
SCHEMBL6799618 0.81 TYR (0.46) TYRMEN1USP2GAAKMT2A
SCHEMBL7245773 0.72 TYR (0.54) TYRCHRM2CHRM3OPRM1OPRD1
SCHEMBL7245757 0.72 TYR (0.54) TYRCHRM2CHRM3OPRM1OPRD1
SCHEMBL5619797 0.72 TYR (0.47) TYRMEN1KMT2ACHRM2CHRM3
SCHEMBL5619802 0.72 TYR (0.47) TYRMEN1KMT2ACHRM2CHRM3
SCHEMBL6810668 0.70 CLK1 (0.42) TYRPDK1
SCHEMBL6810669 0.70 CLK1 (0.42) TYRPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030190298-A1 Resorcinol derivatives BRADLEY STUART E (GB) 2003-10-09 US claimed
US-6797731-B2 USE AS SKIN LIGHTENING AGENTS PFIZER INC. 2004-09-28 US disclosed
US-20030190298-A1 Resorcinol derivatives BRADLEY STUART E (GB) 2003-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030190298-A1 Resorcinol derivatives LRAT, NQO1, ALDH1A2 TYR 8/4885MEN1 2440/4885USP2 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.