Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.41 |
| ▸ | UBE2M | P61081 | 2/20 | 0.41 |
| ▸ | AGER | Q15109 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245773 | 1.00 | TYR (0.54) | TYRPDK1OPRM1DCUN1D1UBE2M | |
| SCHEMBL6806765 | 0.89 | OPRM1 (0.56) | TYROPRM1DCUN1D1UBE2M | |
| SCHEMBL6804847 | 0.89 | OPRM1 (0.56) | TYROPRM1DCUN1D1UBE2M | |
| SCHEMBL6810113 | 0.86 | TYR (0.47) | TYRPDK1DCUN1D1UBE2M | |
| SCHEMBL6810116 | 0.86 | TYR (0.47) | TYRPDK1DCUN1D1UBE2M | |
| SCHEMBL4799331 | 0.81 | AGER (0.44) | OPRM1DCUN1D1UBE2MAGERMTNR1A | |
| SCHEMBL4799335 | 0.81 | AGER (0.44) | OPRM1DCUN1D1UBE2MAGERMTNR1A | |
| SCHEMBL3370759 | 0.80 | AGER (0.55) | OPRM1DCUN1D1AGERMTNR1ACHRM2 | |
| SCHEMBL5619797 | 0.79 | TYR (0.47) | TYRPDK1OPRM1CHRM2CHRM3 | |
| SCHEMBL5619802 | 0.79 | TYR (0.47) | TYRPDK1OPRM1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541473-B2 | Use as skin lightening agents; 4-(1,4-Dioxaspiro(4.5)dec-8-yl)-1,3-benzenediol for example | WARNER LAMBERT COMPANY | 2003-04-01 | — | — | US | disclosed |