Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803422 | 0.81 | CTSS (0.52) | KCNA5KCNE1SMN1; SMN2CTSS | |
| SCHEMBL20217274 | 0.79 | KCNA5 (0.41) | KCNA5KDM4EKCNE1ALDH1A1HIF1A | |
| SCHEMBL6808909 | 0.77 | SMN1; SMN2 (0.38) | KCNA5KDM4EKCNE1ALDH1A1HDAC6 | |
| SCHEMBL14873381 | 0.77 | KCNA5 (0.42) | KCNA5KDM4EKCNE1ALDH1A1HDAC6 | |
| SCHEMBL6802479 | 0.76 | CTSS (0.43) | KCNA5KDM4EKCNE1ALDH1A1HDAC6 | |
| SCHEMBL6808965 | 0.76 | TSHR (0.47) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL20217149 | 0.76 | KCNA5 (0.41) | KCNA5KDM4EKCNE1ALDH1A1HIF1A | |
| SCHEMBL23109247 | 0.76 | KCNA5 (0.47) | KCNA5KDM4EKCNE1ALDH1A1CYP1A2 | |
| SCHEMBL19332957 | 0.76 | KCNA5 (0.47) | KCNA5KDM4EKCNE1ALDH1A1CYP1A2 | |
| SCHEMBL6850515 | 0.76 | KCNA5 (0.47) | KCNA5KDM4EKCNE1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | KCNA5 759/4885KDM4E 3172/4885KCNE1 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.