Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803422 | 0.86 | CTSS (0.52) | NPC1RAB9ASMN1; SMN2CTSS | |
| SCHEMBL6802479 | 0.84 | CTSS (0.43) | NPC1RAB9ACTSSMEN1KMT2A | |
| SCHEMBL20851538 | 0.77 | TSHR (0.55) | TSHRNPC1ALDH1A1TDP1CASR | |
| SCHEMBL6807801 | 0.76 | KCNA5 (0.39) | TSHRSMN1; SMN2CTSSMEN1KMT2A | |
| SCHEMBL6798043 | 0.73 | OPRK1 (0.40) | TSHRNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL20217274 | 0.72 | KCNA5 (0.41) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13822727 | 0.72 | KMT2A (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6808220 | 0.72 | ROCK2 (0.42) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28663870 | 0.72 | TDP1 (0.59) | TSHRHTTMEN1KMT2ATDP1 | |
| SCHEMBL28663869 | 0.72 | TDP1 (0.59) | TSHRHTTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | TSHR 1578/4885NPC1 2721/4885RAB9A 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.