Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807914 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19KCNH2IDO1 | |
| SCHEMBL6807910 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19KCNH2IDO1 | |
| SCHEMBL2875990 | 0.85 | IDO1 (0.42) | IDO1ABCB1KCNA5 | |
| SCHEMBL2875994 | 0.85 | IDO1 (0.42) | IDO1ABCB1KCNA5 | |
| SCHEMBL6807009 | 0.84 | KCNH2 (0.49) | KCNH2IDO1MAPTPOLBKMT2A | |
| SCHEMBL6807010 | 0.84 | KCNH2 (0.49) | KCNH2IDO1MAPTPOLBKMT2A | |
| SCHEMBL6922866 | 0.84 | KCNH2 (0.49) | KCNH2IDO1MAPTPOLBKMT2A | |
| SCHEMBL2882292 | 0.83 | KCNA5 (0.47) | CYP1A2CYP2C9CYP2C19KCNH2L3MBTL1 | |
| SCHEMBL6269528 | 0.83 | KCNA5 (0.47) | CYP1A2CYP2C9CYP2C19KCNH2L3MBTL1 | |
| Methane SCHEMBL11192435 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809114-B2 | ANTIARRHYTHMIC AGENTS; SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-7-NITRO-4-N-PENTYLAMINO-2H-1 -BENZOPYRAN-3-OL | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| EP-1360182-B1 | 4-AMINOBENZOPYRAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-20040068002-A1 | 4-aminobenzopyran derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1360182-A1 | 4-AMINOBENZOPYRAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002064581-A1 | 4-AMINOBENZOPYRAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068002-A1 | 4-aminobenzopyran derivatives | CYP2D6, KCNH1, CYP2B6 | CYP1A2 47/4885CYP2C9 49/4885CYP2C19 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.