Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811829 | 0.87 | HDAC1 (0.42) | PDK1PDK2PDK3PDK4SRD5A1 | |
| SCHEMBL6816345 | 0.86 | ALDH1A1 (0.47) | PDK1PDK2PDK3PDK4HDAC1 | |
| SCHEMBL6812162 | 0.85 | HDAC1 (0.47) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL6811518 | 0.84 | HDAC1 (0.59) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL2759073 | 0.82 | TP53 (0.58) | PDK1PDK2PDK3PDK4SRD5A1 | |
| SCHEMBL6808719 | 0.80 | HDAC1 (0.45) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL847263 | 0.80 | PDK1 (0.50) | PDK1PDK2PDK3PDK4SRD5A1 | |
| SCHEMBL31476414 | 0.80 | HDAC1 (0.57) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL19889063 | 0.79 | PDK1 (0.60) | PDK1PDK2PDK3PDK4SRD5A1 | |
| SCHEMBL10816704 | 0.78 | HSD17B10 (0.51) | PDK1PDK2PDK3PDK4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | PDK1 2940/4885PDK2 3608/4885PDK3 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.