Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479512 | 0.94 | MAPT (0.35) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL316146 | 0.90 | THRB (0.32) | — | |
| Hydrochloric Acid SCHEMBL8006256 | 0.89 | THRB (0.32) | — | |
| Hydrochloric Acid SCHEMBL2219432 | 0.89 | THRB (0.32) | — | |
| SCHEMBL28256376 | 0.89 | THRB (0.32) | — | |
| SCHEMBL21328421 | 0.89 | THRB (0.32) | — | |
| Water SCHEMBL28074687 | 0.87 | THRB (0.31) | — | |
| SCHEMBL27561056 | 0.87 | TP53 (0.36) | MAPTSMN1; SMN2MEN1KMT2A | |
| Biphenyl SCHEMBL9775373 | 0.87 | TP53 (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL27566410 | 0.84 | MEN1 (0.37) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101550077-B | Manufacturing method of bicyclohexyl derivative | FUJI PHOTO FILM CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-101550077-A | Manufacturing method of bicyclohexyl derivative | FUJI PHOTO FILM CO LTD (JP) | 2009-10-07 | — | — | CN | disclosed |
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | JOHNSON CHRISTOPHER NORBERT (GB) | 2004-04-01 | — | — | US | disclosed |
| EP-1305304-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | CNR1, GPR3, CCKAR | MAPT 4260/4885SMN1; SMN2 4533/4885KDM4E 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.