Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.50 |
| ▸ | NAAA | Q02083 | 4/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752705 | 0.94 | MIF (0.48) | MIFNAAANOS1MEN1KMT2A | |
| SCHEMBL8446895 | 0.92 | MIF (0.46) | MIFNAAANOS1MEN1KMT2A | |
| SCHEMBL425325 | 0.86 | MIF (0.67) | MIFNAAAHTR3A | |
| SCHEMBL6804290 | 0.86 | MIF (0.50) | MIFNAAANOS1MEN1KMT2A | |
| SCHEMBL11240241 | 0.85 | NAAA (0.68) | MIFNAAAHTR3A | |
| SCHEMBL4332687 | 0.85 | NAAA (0.68) | MIFNAAAHTR3A | |
| SCHEMBL1006435 | 0.85 | NAAA (0.68) | MIFNAAAHTR3A | |
| SCHEMBL380832 | 0.85 | NAAA (0.68) | MIFNAAAHTR3A | |
| SCHEMBL21248287 | 0.84 | HTR3E (0.51) | MIFHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL331162 | 0.84 | MIF (0.52) | MIFNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8848288-B2 | Composite optical articles | PPG INDUSTRIES OHIO, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120224139-A1 | COMPOSITE OPTICAL ARTICLES | PPG INDUSTRIES OHIO, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-6733887-B2 | Photochromic coated high impact resistant articles | PPG INDUSTRIES OHIO, INC. | 2004-05-11 | — | — | US | disclosed |
| US-6531076-B2 | Poly(urea-urethane) copolymers; impact strength | PPG INDUSTRIES OHIO, INC. | 2003-03-11 | — | — | US | disclosed |
| US-20030044620-A1 | Non-elastomeric poly(urea-urethane) substrate having free isocyanato surface groups and at least a partial coating of a photochromic polymeric coating; lenses | PPG INDUSTRIES OHIO, INC. | 2003-03-06 | — | — | US | disclosed |
| US-20010050356-A1 | Photochromic organic resin composition | TRANSITIONS OPTICAL LIMITED (IE) | 2001-12-13 | — | — | US | disclosed |