Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251847 | 0.88 | ALDH1A1 (0.42) | CYP1A2CYP2A6ALDH1A1CYP1B1BRD1 | |
| SCHEMBL4695580 | 0.85 | ALDH1A1 (0.38) | CYP1A2CYP2A6ALDH1A1CYP1B1BRD1 | |
| SCHEMBL9055556 | 0.83 | ALDH1A1 (0.41) | CYP1A2CYP2A6ALDH1A1CYP1B1BRD1 | |
| SCHEMBL17151500 | 0.82 | ALDH1A1 (0.48) | CYP1A2CYP2A6ALDH1A1CYP1B1BRD1 | |
| SCHEMBL29378790 | 0.79 | CYP1A2 (0.67) | CYP1A2CYP2A6ALDH1A1L3MBTL1TSHR | |
| SCHEMBL598068 | 0.79 | CYP1A2 (0.67) | CYP1A2CYP2A6ALDH1A1L3MBTL1TSHR | |
| SCHEMBL9056547 | 0.76 | TDP1 (0.50) | CYP1A2ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL31307958 | 0.75 | CYP1A2 (0.68) | CYP1A2CYP2A6ALDH1A1L3MBTL1TSHR | |
| SCHEMBL570484 | 0.75 | CYP1A2 (0.68) | CYP1A2CYP2A6ALDH1A1L3MBTL1TSHR | |
| SCHEMBL7836756 | 0.75 | CYP1A2 (0.68) | CYP1A2CYP2A6ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024304-B2 | Naphthalene derivative, organic material including the same, and organic electroluminescent device including the same | DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2015-05-05 | — | — | US | disclosed |
| US-20140299849-A1 | NAPHTHALENE DERIVATIVE, ORGANIC MATERIAL INCLUDING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2014-10-09 | — | — | US | disclosed |
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | CYP1A2 48/4885CYP2A6 39/4885ALDH1A1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.