Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617913 | 0.82 | SRC (0.45) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6281430 | 0.81 | LMNA (0.46) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6451939 | 0.79 | CYP2D6 (0.42) | CYP2D6SRCLMNAMAPK1GSR | |
| SCHEMBL11883845 | 0.79 | CYP2D6 (0.57) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL6451941 | 0.79 | CYP2D6 (0.42) | CYP2D6SRCLMNAMAPK1GSR | |
| SCHEMBL4563568 | 0.79 | CYP2D6 (0.57) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL14935824 | 0.79 | CYP2D6 (0.42) | CYP2D6SRCLMNAMAPK1GSR | |
| SCHEMBL3072376 | 0.79 | CYP2D6 (0.57) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL1586226 | 0.79 | CYP2D6 (0.39) | CYP2D6LMNAKMT2AMEN1 | |
| SCHEMBL18193017 | 0.78 | GSR (0.43) | CYP2D6SRCLMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |