SCHEMBL6281430

SCHEMBL6281430

O=[N+]([O-])C(c1ccccc1)C(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
GSR P00390 1/20 0.44
NPC1 O15118 1/20 0.41
ADAM17 P78536 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39
FBP1 P09467 1/20 0.38
ACP3 P15309 1/20 0.38
MEN1 O00255 1/20 0.38
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 2/20 0.37
APOBEC3G Q9HC16 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828130 0.88 ALDH1A1 (0.41) LMNAALDH1A1GSRNPC1ADAM17
SCHEMBL18193017 0.86 GSR (0.43) LMNAALDH1A1GSRNPC1ADAM17
SCHEMBL8094320 0.86 KMT2A (0.42) LMNAALDH1A1GSRNPC1ADAM17
SCHEMBL28497474 0.84 GSR (0.42) LMNAALDH1A1GSRTDP1KMT2A
SCHEMBL28046604 0.83 LMNA (0.41) LMNAALDH1A1GSRTDP1KMT2A
SCHEMBL9617913 0.83 SRC (0.45) LMNAALDH1A1GSRKMT2ACYP2D6
SCHEMBL6809341 0.81 CYP2D6 (0.59) LMNAGSRKMT2ACYP2D6SRC
SCHEMBL14935824 0.80 CYP2D6 (0.42) LMNAGSRCYP2D6SRCDPP4
SCHEMBL513547 0.80 TAAR1 (0.43) GSRNPC1ADAM17TDP1KMT2A
SCHEMBL6451939 0.80 CYP2D6 (0.42) LMNAGSRCYP2D6SRCDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
CN-103877703-A Dual-Core Comprising Zero Gradient Center And Positive Gradient Outer Core Layer ACUSHNET CO 2014-06-25 CN disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
EP-0144015-B1 SELF-EXTINGUISHING COMPOSITIONS BASED ON ETHYLENE VINYLACETATE COPOLYMERS SUITABLE FOR THE PREPARATION OF FOAMED MATERIALS MONTEDIPE S.p.A. (IT) 1988-09-14 EP disclosed
US-4579683-A 5-Cyano-10-isonitroso-10,11-dihydro-5H-dibenz[b,f]azepine CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed
US-4559174-A NITRATION, REDUCTION AND HYDROLYSIS OF 5-CYANO5H-DIBENZ/B,FLAZEPINE CIBA GEIGY CORPORATION (US) 1985-12-17 US disclosed
US-4452738-A Process for the manufacture of 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,]azepine CIBA-GEIGY CORPORATION (US) 1984-06-05 US disclosed