Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.80 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.80 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | NT5E | P21589 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809456 | 1.00 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL14906327 | 1.00 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5354686 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL5354685 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL6660843 | 0.90 | ADORA3 (0.81) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL6660828 | 0.90 | ADORA3 (0.81) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL14903065 | 0.90 | ADORA3 (0.84) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL13454895 | 0.90 | ADORA3 (0.84) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL12221416 | 0.89 | ADORA3 (0.80) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL3950346 | 0.89 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132686-A1 | C2,5'- disubstituted and N6, c2,5'- trisubstituted adenosine derivatives and their different uses | UNIVERSITEIT LEIDEN (NL) | 2004-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132686-A1 | C2,5'- disubstituted and N6, c2,5'- trisubstituted adenosine derivatives and their different uses | ADORA2A, ADORA3, ADORA1 | ADORA3 2/4885ADORA1 3/4885ADORA2A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.