Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.78 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.78 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | NT5E | P21589 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354685 | 1.00 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL6809452 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL14906327 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL6809456 | 0.90 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL3716748 | 0.89 | ADORA1 (0.87) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL12221416 | 0.88 | ADORA3 (0.80) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL3716756 | 0.88 | ADORA1 (0.86) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL3716753 | 0.88 | ADORA1 (0.86) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL14686249 | 0.88 | ADORA1 (0.86) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL472609 | 0.88 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189706-B2 | C2,5′-disubstituted and N6,C2,5′-trisubstituted adenosine derivatives and pharmaceutical compositions containing them | UNIVERSITEIT LEIDEN (NL) | 2007-03-13 | — | — | US | claimed |