Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809445 | 0.89 | RAB9A (0.48) | RAB9APOLBTBXA2RAGTR1AGTR2 | |
| SCHEMBL6813430 | 0.85 | RAB9A (0.45) | RAB9APOLBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL6809503 | 0.83 | RAB9A (0.52) | RAB9APOLBTBXA2RAGTR1AGTR2 | |
| SCHEMBL6809443 | 0.81 | RAB9A (0.50) | RAB9APOLBTBXA2RAGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL6815317 | 0.78 | RAB9A (0.44) | RAB9APOLBAGTR1AGTR2TP53 | |
| SCHEMBL6817794 | 0.76 | RAB9A (0.43) | RAB9APOLBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL6813431 | 0.75 | RAB9A (0.46) | RAB9ATP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6817787 | 0.73 | RAB9A (0.44) | RAB9ATP53SMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6812302 | 0.71 | RAB9A (0.42) | RAB9APOLBTP53ALDH1A1LMNA | |
| SCHEMBL9700305 | 0.70 | TBXA2R (0.82) | RAB9ATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980359-B1 | BENZIMIDAZOLE DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-6114369-A | N-METHYL-N-(1-(4-FLUOROBENZYL)BENZIONIDAZOL-2-YL)-N'-METHYL-N-(3,5 -BIS(TRIFLUOROMETHYL)BENZYLAMINOCARBONYL)-1,3-PROPYLENEDIAMINE HYDROCHLORIDE, FOR EXAMPLE; SUBSTANCE P ANTAGONISTS; ANTIALLERGIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |