Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809487 | 0.88 | GAA (0.62) | SMN1; SMN2NPC1RAB9AAHRGAA | |
| SCHEMBL321291 | 0.86 | ALDH1A1 (0.63) | SMN1; SMN2NPC1GAAHPGDMAPT | |
| SCHEMBL321631 | 0.85 | HIF1A (0.65) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL30368222 | 0.83 | ALDH1A1 (0.66) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL171190 | 0.83 | ALDH1A1 (0.66) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL26274509 | 0.82 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL18328476 | 0.80 | GAA (0.61) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL4203997 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AAHRGAA | |
| SCHEMBL6808206 | 0.79 | NPC1 (0.74) | SMN1; SMN2NPC1RAB9AAHRHPGD | |
| SCHEMBL10755249 | 0.79 | NPC1 (0.74) | SMN1; SMN2NPC1RAB9AAHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | claimed |
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | RCOR3, F2, NCOR2 | SMN1; SMN2 2813/4885NPC1 2490/4885RAB9A 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.