Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | LDHB | P07195 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934481 | 0.91 | AKR1C3 (0.47) | ALDH1A1MAPK1CES2CES1LDHA | |
| SCHEMBL1043699 | 0.86 | NPSR1 (0.49) | CES2CES1EPHX2 | |
| SCHEMBL1566691 | 0.84 | CES2 (0.59) | CES2CES1LDHALDHBPDE2A | |
| SCHEMBL8078579 | 0.84 | HPGD (0.50) | CES2CES1LDHALDHBPDE2A | |
| SCHEMBL6676161 | 0.84 | CES2 (0.59) | CES2CES1LDHALDHBPDE2A | |
| SCHEMBL1566692 | 0.84 | CES2 (0.59) | CES2CES1LDHALDHBPDE2A | |
| SCHEMBL8084530 | 0.84 | CES2 (0.46) | CES2CES1LDHALDHBPDE2A | |
| SCHEMBL3100510 | 0.82 | CYP1A1 (0.50) | ALDH1A1MAPK1CES2CES1LDHA | |
| SCHEMBL3964967 | 0.82 | CES2 (0.45) | CES2CES1LDHALDHBPDE2A | |
| SCHEMBL12282201 | 0.82 | CES2 (0.45) | CES2CES1LDHALDHBPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209202-A1 | Fluorinated oxyvinyl compounds | HONEYWELL INTERNATIONAL INC. | 2004-10-21 | — | — | US | disclosed |
| US-6743943-B2 | USEFUL IN MAKING PROTECTIVE COATINGS, RELEASE COATINGS, SURFACTANTS, ANTICORROSION AGENTS, AND ANTIOXIDIZING AGENTS FOR FIBER OPTICS, WAVEGUIDES; PHOTOCURING | HONEYWELL INTERNATIONAL INC. | 2004-06-01 | — | — | US | disclosed |
| US-20010034458-A1 | Polymerizable halogenated vinyl ethers | ALLIEDSIGNAL INC. | 2001-10-25 | — | — | US | disclosed |
| EP-1140759-A1 | POLYMERIZABLE HALOGENATED VINYL ETHERS | AlliedSignal Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037403-A1 | POLYMERIZABLE HALOGENATED VINYL ETHERS | ALLIEDSIGNAL INC. (US) | 2000-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034458-A1 | Polymerizable halogenated vinyl ethers | NCEH1, ECH1, CFH | ALDH1A1 2215/4885MAPK1 2155/4885CES2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.