Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818430 | 0.84 | FOLH1 (0.61) | FFAR4KDM4EFFAR1MTNR1AMTNR1B | |
| SCHEMBL6813896 | 0.82 | MAOB (0.50) | FFAR4 | |
| SCHEMBL6807640 | 0.82 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2FFAR4KDM4EHPGD | |
| SCHEMBL2172626 | 0.81 | ABCB1 (0.39) | RAB9ASMN1; SMN2FFAR4CYP1A2MEN1 | |
| SCHEMBL2173652 | 0.81 | ABCB1 (0.38) | RAB9ASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL6812786 | 0.79 | HTT (0.49) | FFAR4KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6809815 | 0.79 | FOLH1 (0.49) | SMN1; SMN2FFAR4KDM4EHPGDFFAR1 | |
| SCHEMBL1995693 | 0.78 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL10092244 | 0.78 | RAB9A (0.45) | RAB9ASMN1; SMN2KDM4EHPGDTLR9 | |
| SCHEMBL7108030 | 0.78 | FFAR4 (0.45) | RAB9ASMN1; SMN2FFAR4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |