SCHEMBL6813896

SCHEMBL6813896

COCOCCc1ccc(OCc2ccccc2)c(C#N)c1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
XDH P47989 4/20 0.46
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
PGGT1B P53609 1/20 0.43
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499877 0.91 MAOB (0.54) MAOBXDHFNTAFNTBPGGT1B
SCHEMBL6809786 0.82 RAB9A (0.46) FFAR4
SCHEMBL6818430 0.79 FOLH1 (0.61) FFAR4
SCHEMBL6809815 0.77 FOLH1 (0.49) FFAR4
SCHEMBL6812786 0.77 HTT (0.49) FFAR4
SCHEMBL9430700 0.77 MAOB (0.68) MAOBXDH
SCHEMBL22498605 0.76 MAOB (0.70) MAOBXDH
SCHEMBL6818076 0.75 CYP2D6 (0.42) XDH
SCHEMBL27303023 0.75 MAOB (0.56) MAOBXDHFNTAFNTBPGGT1B
SCHEMBL9431122 0.74 MAOB (0.72) MAOBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1242983-C Phenoxyacetic acid derivatives and medicinal compositions containing the same KISSEI PHARMACEUTICAL (JP) 2006-02-22 CN disclosed
EP-1095932-B1 PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME KISSEI PHARMACEUTICAL (JP) 2004-05-19 EP disclosed
US-6538152-B1 Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment KISSEI PHARMACEUTICAL CO., LTD. (JP) 2003-03-25 US disclosed
CN-1308603-A Phenoxyacetic acid derivatives and medicinal compositions containing the same KISSEI PHARMACEUTICAL (JP) 2001-08-15 CN disclosed
EP-1095932-A1 PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME Kissei Pharmaceutical Co., Ltd. (JP) 2001-05-02 EP disclosed