Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267075 | 0.85 | KMT2A (0.53) | FOLH1PARP1CYP4F2CYP4A11FFAR4 | |
| SCHEMBL10865469 | 0.84 | FOLH1 (0.52) | FOLH1PARP1FFAR4FFAR1HTT | |
| SCHEMBL6809837 | 0.84 | FOLH1 (0.54) | FOLH1CYP4F2CYP4A11FFAR4FFAR1 | |
| SCHEMBL6812441 | 0.83 | FOLH1 (0.53) | FOLH1CYP4F2CYP4A11FFAR4FFAR1 | |
| SCHEMBL321453 | 0.82 | PARP1 (0.57) | FOLH1PARP1HTTLMNASIRT2 | |
| SCHEMBL6812786 | 0.81 | HTT (0.49) | FOLH1PARP1FFAR4FFAR1HTT | |
| SCHEMBL7131979 | 0.81 | FOLH1 (0.58) | FOLH1PARP1FFAR4FFAR1HTT | |
| SCHEMBL360371 | 0.81 | CYP4F2 (0.63) | CYP4F2CYP4A11FFAR4FFAR1KDM4E | |
| SCHEMBL3729989 | 0.80 | PTGER1 (0.64) | FOLH1PARP1 | |
| SCHEMBL4723723 | 0.80 | LRRK2 (0.58) | FOLH1PARP1LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1242983-C | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| CN-1308603-A | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2001-08-15 | — | — | CN | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |