Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12296058 | 0.91 | BCHE (0.61) | CYP4F2CYP4A11MTNR1AMTNR1BKDM4E | |
| SCHEMBL1322956 | 0.91 | KDM4E (0.64) | CYP4F2CYP4A11MTNR1AMTNR1BKDM4E | |
| SCHEMBL19194585 | 0.90 | LTA4H (0.64) | CYP4F2CYP4A11SLC2A1FFAR4FFAR1 | |
| SCHEMBL30880065 | 0.89 | LTA4H (0.58) | CYP4F2CYP4A11SLC2A1FFAR4FFAR1 | |
| SCHEMBL21657693 | 0.89 | LTA4H (0.58) | CYP4F2CYP4A11SLC2A1FFAR4FFAR1 | |
| SCHEMBL10826260 | 0.87 | LTA4H (0.56) | CYP4F2CYP4A11SLC2A1FFAR4FFAR1 | |
| SCHEMBL584781 | 0.86 | SLC2A1 (0.56) | SLC2A1BCHEMEN1KMT2APOLB | |
| SCHEMBL30280404 | 0.86 | SLC2A1 (0.56) | SLC2A1BCHEMEN1KMT2APOLB | |
| SCHEMBL6813660 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11FFAR4FFAR1KDM4E | |
| SCHEMBL10725217 | 0.85 | FFAR4 (0.72) | CYP4F2CYP4A11FFAR4FFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521286-B | Preparation method and application of compound 3-hydroxy-3 ', 4' -dihydroxy-butyric acid phenethyl ester | 西安交通大学 | 2021-12-28 | — | — | CN | claimed |
| CN-112521286-A | Preparation method and application of compound 3-hydroxy-3 ', 4' -dihydroxy-butyric acid phenethyl ester | 西安交通大学 | 2021-03-19 | — | — | CN | claimed |
| US-20210078932-A1 | 3,4-DIHYDROXYPHENETHYL 3-HYDROXYBUTANOATE, PREPARATION AND USE THEREOF | CHENGDU MEDICAL COLLEGE (CN) | 2021-03-18 | — | — | US | claimed |
| CN-116444569-A | Triphenylhydroxytyrosol and synthesis method thereof and application of triphenylhydroxytyrosol in preparation of medicines for improving aortic endothelial cell functions | 西安交通大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-115850334-A | Triphenylphosphonium-hydroxytyrosol, synthesis method thereof and application thereof in preparing drugs for inhibiting cancer cell proliferation | 西安交通大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-112521286-B | Preparation method and application of compound 3-hydroxy-3 ', 4' -dihydroxy-butyric acid phenethyl ester | 西安交通大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112521286-A | Preparation method and application of compound 3-hydroxy-3 ', 4' -dihydroxy-butyric acid phenethyl ester | 西安交通大学 | 2021-03-19 | — | — | CN | disclosed |
| US-20210078932-A1 | 3,4-DIHYDROXYPHENETHYL 3-HYDROXYBUTANOATE, PREPARATION AND USE THEREOF | CHENGDU MEDICAL COLLEGE (CN) | 2021-03-18 | — | — | US | disclosed |
| US-20210078932-A1 | 3,4-DIHYDROXYPHENETHYL 3-HYDROXYBUTANOATE, PREPARATION AND USE THEREOF | CHENGDU MEDICAL COLLEGE (CN) | 2021-03-18 | — | — | US | disclosed |
| US-10947179-B2 | 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, composition, and method for improving function of aortic endothelial cell | XI'AN JIAOTONG UNIVERSITY (CN) | 2021-03-16 | — | — | US | disclosed |
| US-10947179-B2 | 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, composition, and method for improving function of aortic endothelial cell | XI'AN JIAOTONG UNIVERSITY (CN) | 2021-03-16 | — | — | US | disclosed |
| WO-2012006783-A1 | PROCESS FOR PRODUCTION OF HYDROXYTYROSOL USING ORGANOMETALLIC COMPOUNDS | LONZA LTD (CH) | 2012-01-19 | — | — | WO | disclosed |
| CN-101891595-A | Method for preparing hydroxytyrosol | UNIV SUZHOU | 2010-11-24 | — | — | CN | disclosed |
| CN-101580460-A | Synthesis method of 3, 4-dihydroxy phenylethanol | TAIZHOU ZHIQING CHEMICAL CO LT (CN) | 2009-11-18 | — | — | CN | disclosed |
| US-20050154058-A1 | Method of preparing hydroxytyrosol esters, esters thus obtained and use of same | UNIVERSIDAD DE SEVILLA (ES) | 2005-07-14 | — | — | US | disclosed |
| EP-1541544-A1 | METHOD OF PREPARING HYDROXYTYROSOL ESTERS, ESTERS THUS OBTAINED AND USE OF SAME | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2005-06-15 | — | — | EP | disclosed |
| EP-0781126-B1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON SPA (IT) | 2001-12-12 | — | — | EP | disclosed |
| US-5674909-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | ZAMBON GROUP (IT) | 1997-10-07 | — | — | US | disclosed |
| EP-0781126-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008228-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154058-A1 | Method of preparing hydroxytyrosol esters, esters thus obtained and use of same | HAAO, ACSL3, HACL2 | CYP4F2 2963/4885CYP4A11 327/4885SLC2A1 4154/4885 |
| US-10947179-B2 | 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, composition, and method for improving function of aortic endothelial cell | TFAM, MAVS, ACADVL | CYP4F2 1651/4885CYP4A11 723/4885SLC2A1 2225/4885 |
| US-20210078932-A1 | 3,4-DIHYDROXYPHENETHYL 3-HYDROXYBUTANOATE, PREPARATION AND USE THEREOF | HTR3B, HSD3B1, HTR3C | CYP4F2 147/4885CYP4A11 53/4885SLC2A1 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.