Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853069 | 0.89 | FOLH1 (0.57) | FOLH1FFAR4ALDH1A1HTTMTNR1A | |
| SCHEMBL27820729 | 0.88 | FOLH1 (0.56) | FOLH1FFAR4ALDH1A1HTTMTNR1A | |
| SCHEMBL4416634 | 0.88 | FOLH1 (0.58) | FOLH1FFAR4ALDH1A1HTTMTNR1A | |
| SCHEMBL854248 | 0.85 | FOLH1 (0.59) | FOLH1FFAR4ALDH1A1HTTLMNA | |
| SCHEMBL6809815 | 0.84 | FOLH1 (0.49) | FOLH1FFAR4ALDH1A1HTTMTNR1A | |
| SCHEMBL6809852 | 0.84 | FOLH1 (0.57) | FOLH1CYP4F2CYP4A11FFAR4ALDH1A1 | |
| SCHEMBL10715941 | 0.83 | HPGD (0.55) | FFAR4ALDH1A1HTTMTNR1AMTNR1B | |
| SCHEMBL11094898 | 0.83 | MTNR1A (0.56) | FOLH1FFAR4ALDH1A1HTTMTNR1A | |
| SCHEMBL6812441 | 0.83 | FOLH1 (0.53) | FOLH1CYP4F2CYP4A11FFAR4ALDH1A1 | |
| SCHEMBL8070829 | 0.83 | FOLH1 (0.53) | FOLH1FFAR4ALDH1A1HTTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1242983-C | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| CN-1308603-A | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2001-08-15 | — | — | CN | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |