Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349997 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL3286100 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL9596419 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL5531315 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL27953450 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL4159760 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL3483273 | 0.78 | MEN1 (0.64) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL27953447 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL3482970 | 0.76 | MEN1 (0.61) | ALDH1A1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL14628370 | 0.75 | NPSR1 (0.72) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132809-A1 | Cell adhesion inhibitors | BIOGEN, INC. | 2004-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132809-A1 | Cell adhesion inhibitors | VCAM1, ICAM1, EPCAM | ALDH1A1 631/4885MEN1 3126/4885KMT2A 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.