Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809807 | 0.90 | ALDH1A1 (0.61) | CYP4F2CYP4A11ALDH1A1KMT2ALMNA | |
| SCHEMBL6813693 | 0.88 | ALDH1A1 (0.48) | HTTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9026143 | 0.85 | S1PR1 (0.56) | HTTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2848440 | 0.82 | CYP4F2 (0.59) | CYP4F2CYP4A11HTTALDH1A1KMT2A | |
| SCHEMBL6818066 | 0.82 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6813895 | 0.82 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6813898 | 0.81 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1KMT2AMEN1 | |
| SCHEMBL10759385 | 0.80 | ALOX15 (0.56) | CYP4F2CYP4A11HTTALDH1A1KMT2A | |
| SCHEMBL3689530 | 0.80 | ESR1 (0.51) | CYP4F2CYP4A11ALDH1A1KMT2AMEN1 | |
| SCHEMBL29463785 | 0.79 | ALDH1A1 (0.56) | HTTALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |