Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19600559 | 0.76 | KIF11 (0.40) | CYP3A4CYP2D6SLC6A2TAAR1SMN1; SMN2 | |
| SCHEMBL841941 | 0.74 | TAAR1 (0.34) | LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL11099246 | 0.74 | CYP3A4 (0.46) | CYP3A4MAPTKDM4EADH1BADH1C | |
| SCHEMBL6282747 | 0.71 | HDAC3 (0.36) | CYP3A4MAPTKDM4EIDO1GAA | |
| SCHEMBL3273386 | 0.70 | IDO1 (0.54) | CYP3A4MAPTKDM4EADH1BADH1C | |
| Hydrochloric Acid SCHEMBL23928399 | 0.69 | HDAC3 (0.35) | CYP3A4IDO1GAATAAR1HTT | |
| SCHEMBL3122253 | 0.69 | IDO1 (0.52) | CYP3A4MAPTKDM4EADH1BADH1C | |
| SCHEMBL27946817 | 0.68 | MEN1 (0.38) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL27946821 | 0.68 | CYP3A4 (0.37) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL6907584 | 0.67 | IDO1 (0.50) | CYP3A4MAPTKDM4EADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023818-A1 | Method and product for enhancing the clean-up of hydrocarbon-producing well | HALLIBURTON ENERGY SERVICES, INC. | 2004-02-05 | — | — | US | claimed |
| US-20040023818-A1 | Method and product for enhancing the clean-up of hydrocarbon-producing well | HALLIBURTON ENERGY SERVICES, INC. | 2004-02-05 | — | — | US | disclosed |
| EP-0400916-B1 | 4,5,6,11-Tetrahydrobenzo [6,7]-cycloocta[1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo[6,7]-cycloocta[1,2-b]thiophen-6,11 imines | PFIZER (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5260309-A | 4,5,6,11-tetrahydrobenzo [6,7] cycloocta [1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo [6,7] cycloocta [1,2-b] thiophen-6,11-imines | PFIZER INC. (US) | 1993-11-09 | — | — | US | disclosed |
| WO-1990015060-A1 | 4,5,6,11-TETRAHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES AND 6,11-DIHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES | PFIZER INC. (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400916-A2 | 4,5,6,11-Tetrahydrobenzo [6,7]-cycloocta[1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo[6,7]-cycloocta[1,2-b]thiophen-6,11 imines | PFIZER INC. (US) | 1990-12-05 | — | — | EP | disclosed |