SCHEMBL3273386

SCHEMBL3273386

C[Si](C)(C)NCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.54
THRB P10828 2/20 0.54
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HTT P42858 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH7 P40394 1/20 0.43
ALOX12 P18054 1/20 0.43
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11143459 0.83 ALDH1A1 (0.41) CYP3A4MAPTKDM4EMEN1KMT2A
SCHEMBL6907584 0.81 IDO1 (0.50) IDO1THRBCYP3A4MAPTKDM4E
SCHEMBL11099246 0.79 CYP3A4 (0.46) IDO1THRBCYP3A4MAPTKDM4E
SCHEMBL3122253 0.79 IDO1 (0.52) IDO1THRBCYP3A4MAPTKDM4E
SCHEMBL15135122 0.78 CYP3A4 (0.45) IDO1THRBCYP3A4MAPTKDM4E
SCHEMBL26964162 0.78 CYP3A4 (0.45) IDO1THRBCYP3A4MAPTKDM4E
SCHEMBL11562113 0.76 LMNA (0.52) IDO1KDM4EMEN1KMT2AALDH1A1
SCHEMBL6560133 0.76 ATM (0.58) IDO1CYP3A4MAPTMEN1KMT2A
SCHEMBL19973215 0.76 CYP3A4 (0.43) IDO1THRBCYP3A4MAPTKDM4E
SCHEMBL28924922 0.75 CYP3A4 (0.46) IDO1THRBCYP3A4MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US claimed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP claimed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US claimed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US claimed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US claimed
US-6365643-B1 Photoinitiators for cationic curing TH. GOLDSCHMIDT AG (DE) 2002-04-02 US claimed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP claimed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO claimed
US-12559452-B2 Method for the synthesis of isocyanates CYNIO GmbH (DE) 2026-02-24 US disclosed
US-20250361335-A1 PREPARATION AND METHODS FOR THE MAKING OF AMINE CONTAINING POLYBUTADIENE POLYMERS UNIV BRITISH COLUMBIA (CA) 2025-11-27 US disclosed
CN-119365503-A Process for preparing and producing amine-containing polybutadiene polymers 不列颠哥伦比亚大学 2025-01-24 CN disclosed
EP-4149920-B1 PROCESS FOR THE SYNTHESIS OF ISOCYANATES UNIV FREIBERG TECH BERGAKADEMIE (DE) 2024-07-31 EP disclosed
WO-2023197082-A1 PREPARATION AND METHODS FOR THE MAKING OF AMINE CONTAINING POLYBUTADIENE POLYMERS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-10-19 WO disclosed
CN-112334537-B Propylene polymer composition 住友化学株式会社 2023-07-07 CN disclosed
EP-0355750-A1 Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process WARNER-LAMBERT COMPANY (US) 1990-02-28 EP disclosed
EP-0295401-A2 Process for polymerizing polar compounds WACKER-CHEMIE GMBH (DE) 1988-12-21 EP disclosed
EP-0011370-B1 PROCESS FOR PREPARING 2-CHLOROSULFINYL-AZETIDINONES ELI LILLY AND COMPANY (US) 1982-04-28 EP disclosed
US-4289695-A REACTION OF A PHENICILLIN WITH AN N-CHLORO HALOGENATING AGENT IN PRESENCE OF A CROSSLINKED POLYVINYLPYRIDINE ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
EP-0011370-A1 Process for preparing 2-chlorosulfinyl-azetidinones ELI LILLY AND COMPANY (US) 1980-05-28 EP disclosed
US-4159272-A Process for 2-chlorosulfinylazetidin-4-ones ELI LILLY AND COMPANY (US) 1979-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559452-B2 Method for the synthesis of isocyanates GCN1, SCN7A, GMNN IDO1 651/4885THRB 3205/4885CYP3A4 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.