Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16194521 | 0.89 | GSR (0.59) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL8995618 | 0.85 | GNAI3 (0.50) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL10659244 | 0.84 | GSR (0.50) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL1404247 | 0.83 | GSR (0.61) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL344574 | 0.83 | GSR (0.61) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL20240364 | 0.83 | GSR (0.61) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL1484685 | 0.82 | GNAI3 (0.53) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL8493192 | 0.82 | GSR (0.52) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL3810133 | 0.82 | GSR (0.52) | GSRGNAI3GNAO1GNAI1CPB2 | |
| SCHEMBL3457786 | 0.82 | GSR (0.44) | GSRGNAI3GNAO1GNAI1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061909-B1 | KETO ACID SALTS AND AMINE DERIVATIVES, AND THEIR USE FOR PREPARING MEDICINES | CHIESI S A (FR) | 2002-06-05 | — | — | EP | claimed |
| US-20040127413-A1 | Enteric keto acid and amino acid salts and their use for preparing medicines | AVAYA TECHNOLOGY LLC | 2004-07-01 | — | — | US | disclosed |
| US-6429229-B1 | ADMINISTERING TO TREAT PATHOLOGIES ASSOCIATED WITH SILENT NEURONS (BLADDER, BILE DUCTS, AND DIGESTIVE SYSTEM) | CHIESI S.A. (FR) | 2002-08-06 | — | — | US | disclosed |