SCHEMBL344574

SCHEMBL344574

NCCCC[C@H](N)C(=O)OC(=O)[C@@H](N)CCCCN

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.61
RNPEP Q9H4A4 1/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
DPP7 Q9UHL4 8/20 0.42
DPP8 Q6V1X1 4/20 0.42
DPP9 Q86TI2 4/20 0.42
DPP4 P27487 2/20 0.42
CPB2 Q96IY4 4/20 0.42
FAP Q12884 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1404247 1.00 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL20240364 1.00 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL680614 0.98 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL3825519 0.98 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL2099474 0.98 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL11287494 0.96 GSR (0.57) GSRRNPEPGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL11287492 0.96 GSR (0.57) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL16194521 0.93 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL997560 0.93 GSR (0.52) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL29075853 0.93 GSR (0.52) GSRRNPEPGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118974058-A Preparation method and crystalline form of (6A, 12A) -17-amino-12-methyl-6, 15-bis (trifluoromethyl) -13, 19-dioxa-3,4,18-triazatricyclo [12.3.1.12,5] nonadeca-1 (18), 2,4,14,16-pentaen-6-ol 弗特克斯药品有限公司 2024-11-15 CN claimed
CN-118695873-A Pharmaceutical composition comprising human hyaluronidase PH20 and a drug 阿特根公司 2024-09-24 CN claimed
WO-2024113429-A1 TARGETED BIONIC POLYPEPTIDE NANO DELIVERY CARRIER, NANO NUCLEIC ACID DELIVERY SYSTEM, PREPARATION METHOD THEREFOR, AND USE THEREOF 深圳先进技术研究院 2024-06-06 WO claimed
CN-117534581-A Process for preparing L-lysine monohydrate 湖北葛店人福药用辅料有限责任公司 2024-02-09 CN claimed
CN-116603072-A Method for preparing functionalized nano material by ring-opening polymerization induction of phenylalanine anhydride initiated by water-soluble photosensitizer 大连工业大学 2023-08-18 CN claimed
CN-116196294-A Amphiphilic polyamino acid drug-loaded nano-particle with stimulus responsiveness and preparation method thereof 宁德师范学院 2023-06-02 CN claimed
CN-116139104-A Targeting bionic polypeptide nano delivery carrier, nano nucleic acid delivery system, preparation method and application thereof 深圳先进技术研究院 2023-05-23 CN claimed
CN-114524932-A Amphiphilic triblock polyamino acid copolymer, intermediate, preparation and application 宁德师范学院 2022-05-24 CN claimed
CN-105797140-B Stable formulations of hyaluronan degrading enzymes 哈洛齐梅公司 2020-08-11 CN claimed
US-9993529-B2 Stable formulations of a hyaluronan-degrading enzyme HALOZYME, INC. (US) 2018-06-12 US claimed
CN-103100093-A Load small interfering RNA nanoscale lipid microbubble ultrasonic contrast agent and preparation method THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY 2013-05-15 CN claimed
US-20130022588-A1 Stable formulations of a hyaluronan-degrading enzyme related applications HALOZYME THERAPEUTICS, INC. 2013-01-24 US claimed
US-20130011378-A1 Stable formulations of a hyaluronan-degrading enzyme HALOZYME THERAPEUTICS, INC. 2013-01-10 US claimed
WO-2012174478-A2 STABLE FORMULATIONS OF A HYALURONAN-DEGRADING ENZYME HALOZYME, INC. (US) 2012-12-20 WO claimed
CN-101044188-A Process for preparing glatiramer SANDOZ AG (CH) 2007-09-26 CN claimed
CN-1308690-C Novel method and kit for sequencing polypeptides PROCTER & GAMBLE (US) 2007-04-04 CN claimed
CN-1551984-A Novel method and kit for sequencing polypeptides 2004-12-01 CN claimed
EP-0182356-B2 Nutrient compositions MONTEFIORE HOSPITAL ASS OF WES (US) 1998-08-05 EP claimed
US-5034377-A Dipeptides and tripeptides for use as nutrients in diets MONTEFIORE HOSPITAL ASSOCIATION OF WESTERN PENNSYLVANIA (US) 1991-07-23 US claimed
EP-0182356-A2 Nutrient compositions The Montefiore Hospital Association of Western Pennsylvania (US) 1986-05-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130022588-A1 Stable formulations of a hyaluronan-degrading enzyme related applications IDE, MMP20, IDUA GSR 4631/4885RNPEP 36/4885GNAI3 4512/4885
US-20130011378-A1 Stable formulations of a hyaluronan-degrading enzyme IDE, IDUA, MMP20 GSR 4741/4885RNPEP 39/4885GNAI3 4432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.