Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 9/20 | 0.63 |
| ▸ | PKN2 | Q16513 | 9/20 | 0.63 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.63 |
| ▸ | PLK4 | O00444 | 1/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.63 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | PIM1 | P11309 | 1/20 | 0.63 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.63 |
| ▸ | PRKACA | P17612 | 1/20 | 0.63 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.63 |
| ▸ | CLK2 | P49760 | 1/20 | 0.63 |
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
| ▸ | PRKX | P51817 | 1/20 | 0.63 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.63 |
| ▸ | STK3 | Q13188 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579908 | 0.88 | PARP1 (0.61) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL6840234 | 0.87 | ALDH1A1 (0.52) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL2149454 | 0.86 | PARP1 (0.63) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL6806964 | 0.85 | PKN1 (0.65) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL6805689 | 0.85 | PKN1 (0.49) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL6809910 | 0.85 | PKN1 (0.46) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL7583436 | 0.84 | PARP1 (0.66) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL3575391 | 0.81 | DHODH (0.47) | PKN1PKN2CHEK2PLK4MAPK13 | |
| SCHEMBL3585144 | 0.81 | PARP1 (0.64) | PLK4MAP4K4PIM1AURKBMKNK2 | |
| SCHEMBL6805361 | 0.81 | PDPK1 (0.43) | PKN1PKN2CHEK2PLK4MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |