SCHEMBL6810129

SCHEMBL6810129

CCc1c(Oc2ccc(S(=O)(=O)c3ccc(C[C@@H](C)N)cc3)cc2)cccc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ITGB1 P05556 1/20 0.38
ITGA4 P13612 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
SLC6A4 P31645 1/20 0.38
CARM1 Q86X55 3/20 0.38
PRMT6 Q96LA8 3/20 0.38
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TARS1 P26639 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6810123 1.00 POLB (0.39) POLBAPEX1CTDSP1L3MBTL1ITGB1
SCHEMBL6805226 0.83 ACACB (0.43) L3MBTL1ITGB1ITGA4TDP1ALDH1A1
SCHEMBL6805230 0.83 ACACB (0.43) L3MBTL1ITGB1ITGA4TDP1ALDH1A1
SCHEMBL6804598 0.82 LTB4R2 (0.40) ITGB1ITGA4SLC6A4
SCHEMBL6809999 0.79 SYK (0.41) ITGB1ITGA4SMN1; SMN2
SCHEMBL6804172 0.77 ABCC9 (0.39) L3MBTL1ITGB1ITGA4TDP1
SCHEMBL6804169 0.77 ABCC9 (0.39) L3MBTL1ITGB1ITGA4TDP1
SCHEMBL6682568 0.76 AKR1C3 (0.52) POLBAPEX1CTDSP1L3MBTL1TDP1
SCHEMBL6539936 0.73 ANPEP (0.51) L3MBTL1TDP1SLC6A4KMT2A
SCHEMBL6539185 0.73 ALDH1A1 (0.68) L3MBTL1SLC6A4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040106653-A1 Aminoalcohol derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040106653-A1 Aminoalcohol derivatives FANCD2, FANCI, HRH2 POLB 972/4885APEX1 1235/4885CTDSP1 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.