Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110437 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNACYP19A1L3MBTL1MEN1 | |
| SCHEMBL13176247 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNACYP19A1L3MBTL1MEN1 | |
| SCHEMBL836917 | 0.82 | ESR1 (0.53) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL6810140 | 0.82 | CES1 (0.51) | ALDH1A1LMNACYP19A1L3MBTL1MEN1 | |
| SCHEMBL6810221 | 0.82 | CES1 (0.51) | ALDH1A1LMNACYP19A1L3MBTL1MEN1 | |
| SCHEMBL7112205 | 0.81 | HSD11B1 (0.46) | ALDH1A1LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL15279922 | 0.81 | HSPB1 (0.59) | ALDH1A1LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL2815328 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNACYP19A1L3MBTL1MEN1 | |
| SCHEMBL10506969 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNACYP19A1L3MBTL1MEN1 | |
| SCHEMBL8198662 | 0.79 | APP (0.57) | ALDH1A1LMNAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507616-B1 | Process for the preparation of trisubstituted ureas by reductive carbonylation | ARCO CHEM TECH (US) | 1996-02-07 | — | — | EP | claimed |
| US-5241118-A | Reacting nitroarene with carbon monoxide | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1993-08-31 | — | — | US | claimed |
| EP-0507616-A1 | Process for the preparation of trisubstituted ureas by reductive carbonylation | ARCO Chemical Technology, L.P. (US) | 1992-10-07 | — | — | EP | claimed |
| EP-0507616-B1 | Process for the preparation of trisubstituted ureas by reductive carbonylation | ARCO CHEM TECH (US) | 1996-02-07 | — | — | EP | disclosed |