Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | PPARG | P37231 | 5/20 | 0.71 |
| ▸ | PPARD | Q03181 | 4/20 | 0.71 |
| ▸ | PPARA | Q07869 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.71 |
| ▸ | FABP4 | P15090 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971537 | 0.98 | PPARG (0.73) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL258342 | 0.96 | ALDH1A1 (0.74) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL3509409 | 0.94 | TOP1 (0.69) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL6811185 | 0.93 | ALDH1A1 (0.69) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL2515811 | 0.91 | PPARG (0.68) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL18340149 | 0.91 | TERT (0.71) | PPARGPPARDPPARALMNACYP19A1 | |
| SCHEMBL8367776 | 0.91 | TERT (0.71) | PPARGPPARDPPARALMNACYP19A1 | |
| SCHEMBL16006989 | 0.91 | TERT (0.71) | PPARGPPARDPPARALMNACYP19A1 | |
| SCHEMBL258101 | 0.91 | TERT (0.71) | PPARGPPARDPPARALMNACYP19A1 | |
| SCHEMBL18340144 | 0.91 | TERT (0.71) | PPARGPPARDPPARALMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790056-B1 | USE OF COMPOSITION FOR PREVENTING OR TREATING DISEASES CAUSED BY ABNORMALITIES IN CARTILAGE TISSUES | SUNTORY LTD (JP) | 2004-11-10 | — | — | EP | claimed |