SCHEMBL6812409

SCHEMBL6812409

Cc1c(NC=O)c(=O)n(-c2ccccc2)n1C

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2D6 P10635 1/20 0.64
GAA P10253 10/20 0.63
TSHR P16473 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
ALDH1A1 P00352 6/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
MAPT P10636 6/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
LMNA P02545 1/20 0.59
RAB9A P51151 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
GLA P06280 1/20 0.57
USP2 O75604 1/20 0.56
ALOX15 P16050 1/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399779 0.88 BCHE (0.51) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL23402925 0.87 ALDH1A1 (0.58) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL537958 0.82 KDM4E (0.69) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL23401512 0.82 ALDH1A1 (0.53) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL23402983 0.82 ALDH1A1 (0.53) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL23403198 0.81 TSHR (0.45) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL18000055 0.81 KDM4E (0.68) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL4447238 0.81 KDM4E (0.68) KDM4ECYP1A2CYP2D6GAATSHR
SCHEMBL8651089 0.81 KDM4E (0.68) KDM4ECYP1A2CYP2D6GAATSHR
Magnesium SCHEMBL29732237 0.81 KDM4E (0.68) KDM4ECYP1A2CYP2D6GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350249-A Purification method of 4-methylamino antipyrine 河北冀衡药业股份有限公司 2025-01-24 CN claimed
CN-117143020-A Preparation method of analgin with content of analgin impurity 4-N sodium methylenesulfonate analgin controlled 河北冀衡药业股份有限公司 2023-12-01 CN claimed
CN-113248440-B Synthetic method of 4-formamido antipyrine 河北冀衡药业股份有限公司 2022-11-04 CN claimed
CN-113248440-A Synthetic method of 4-formamido antipyrine 河北冀衡药业股份有限公司 2021-08-13 CN claimed
CN-107817306-B Method for simultaneously detecting 64 veterinary drug residues in aquatic product 中山出入境检验检疫局检验检疫技术中心 2020-06-19 CN claimed
CN-111303036-A Synthetic method of analgin impurity 山东新华制药股份有限公司 2020-06-19 CN claimed
CN-107255686-B Analysis method for determining multi-veterinary drug residues in aquaculture water 中山出入境检验检疫局检验检疫技术中心 2020-03-27 CN claimed
CN-116514718-B Hybridoma cell strain, analgin residue marker 4-methylamino antipyrine monoclonal antibody secreted by hybridoma cell strain and application of analgin residue marker 河南农业大学 2026-01-30 CN disclosed
CN-119350249-A Purification method of 4-methylamino antipyrine 河北冀衡药业股份有限公司 2025-01-24 CN disclosed
CN-119350249-A Purification method of 4-methylamino antipyrine 河北冀衡药业股份有限公司 2025-01-24 CN disclosed
CN-117143020-A Preparation method of analgin with content of analgin impurity 4-N sodium methylenesulfonate analgin controlled 河北冀衡药业股份有限公司 2023-12-01 CN disclosed
CN-117143020-A Preparation method of analgin with content of analgin impurity 4-N sodium methylenesulfonate analgin controlled 河北冀衡药业股份有限公司 2023-12-01 CN disclosed
CN-114315723-B Analgin residual marker hapten and artificial antigen as well as preparation methods and applications thereof 中国农业大学 2023-08-08 CN disclosed
EP-1150660-B1 PHARMACEUTICAL EFFERVESCENT FORMULATION CONTAINING METAMIZOL HEXAL AG (DE) 2004-01-21 EP disclosed
EP-1150660-A1 PHARMACEUTICAL EFFERVESCENT FORMULATION CONTAINING METAMIZOL HEXAL AG (DE) 2001-11-07 EP disclosed
WO-2000066088-A1 CONTROLLED RELEASE PHARMACEUTICAL PREPARATION CONTAINING METAMIZOLE HEXAL AG (DE) 2000-11-09 WO disclosed
WO-2000047189-A1 PHARMACEUTICAL EFFERVESCENT FORMULATION CONTAINING METAMIZOL HEXAL AG (DE) 2000-08-17 WO disclosed
US-5760216-A REACTING DRUG SAMPLE WITH SYNTHETIC METALLOPORPHYRIN, OXIDIZING AGENT, SOLVENT TO FORM OXIDATION PRODUCT ABBOTT LABORATORIES (US) 1998-06-02 US disclosed
EP-0781261-A2 USE OF SYNTHETIC METALLOPORPHYRINS FOR PREPARATION AND PREDICTION OF DRUG METABOLITES Abbott Laboratories (US) 1997-07-02 EP disclosed
WO-1996008455-A2 USE OF SYNTHETIC METALLOPORPHYRINS FOR PREPARATION AND PREDICTION OF DRUG METABOLITES ABBOTT LABORATORIES (US) 1996-03-21 WO disclosed