Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | S100A4 | P26447 | 2/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28163932 | 0.87 | KMT2A (0.47) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL28104917 | 0.87 | TSHR (0.56) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL1130962 | 0.87 | VCAM1 (0.53) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL1131161 | 0.82 | ALDH1A1 (0.59) | TDP1KMT2AMEN1CA2ALDH1A1 | |
| SCHEMBL1131516 | 0.82 | ALDH1A1 (0.45) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL9877267 | 0.82 | ERN1 (0.42) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL31294386 | 0.80 | TDP1 (0.54) | TDP1GPR35KMT2AMEN1CA2 | |
| Sulfamide SCHEMBL28235502 | 0.79 | KMT2A (0.61) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL1130917 | 0.79 | TDP1 (0.39) | TDP1GPR35KMT2AMEN1CA2 | |
| SCHEMBL23668290 | 0.78 | TDP1 (0.52) | TDP1GPR35KMT2AMEN1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | TORAY INDUSTRIES, INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| CN-1458922-A | Urea derivative and adhesive-molecule inhibitor containing same as ctive ingredient | TORAY INDUSTRIES (JP) | 2003-11-26 | — | — | CN | disclosed |
| EP-1323709-A1 | UREA DERIVATIVE AND ADHESIVE-MOLECULE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | ICAM1, VCAM1, EPCAM | TDP1 4288/4885GPR35 699/4885KMT2A 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.