Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.56 |
| ▸ | PDE4A | P27815 | 12/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761057 | 0.94 | PDE4D (0.49) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL8846224 | 0.88 | RECQL (0.55) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL7151110 | 0.82 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL20064269 | 0.82 | PDE4A (0.53) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL7418541 | 0.82 | PDE4A (0.52) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2958828 | 0.82 | RECQL (0.60) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL1028306 | 0.82 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL15904183 | 0.80 | CSNK2A1 (0.48) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL7376963 | 0.79 | HTT (0.52) | PDE4DPDE4APDE4BPDE4CRECQL | |
| SCHEMBL15903786 | 0.79 | CSNK2A1 (0.47) | PDE4DPDE4APDE4BPDE4CRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016596-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS PDE-IV INHIBITORS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-02-26 | — | — | WO | disclosed |