Biphenyl

Biphenyl

SCHEMBL6812918

COC(=O)c1ccccc1OC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.68
KMT2A Q03164 3/20 0.55
HTT P42858 1/20 0.55
MAPT P10636 3/20 0.54
HSD17B10 Q99714 5/20 0.53
KDM4E B2RXH2 4/20 0.53
HPGD P15428 2/20 0.53
SLC6A4 P31645 2/20 0.53
TSHR P16473 3/20 0.50
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 2/20 0.49
CFTR P13569 1/20 0.49
ATM Q13315 2/20 0.48
ALOX15 P16050 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3932901 0.95 SLC6A3 (0.74) SLC6A3KMT2AHTTMAPTHSD17B10
SCHEMBL1638898 0.85 SLC6A3 (0.54) SLC6A3KMT2AHTTMAPTHSD17B10
SCHEMBL1638900 0.85 SLC6A3 (0.61) SLC6A3KMT2AHTTMAPTHSD17B10
Dimethyl Phthalate SCHEMBL3686830 0.83 TSHR (0.63) SLC6A3KMT2AMAPTHSD17B10KDM4E
Biphenyl SCHEMBL5706044 0.82 TSHR (0.61) SLC6A3KMT2AMAPTHSD17B10KDM4E
SCHEMBL5706028 0.82 SLC6A3 (0.77) SLC6A3KMT2AHTTMAPTHSD17B10
SCHEMBL29551673 0.82 SLC6A3 (0.71) SLC6A3KMT2AHTTMAPTHSD17B10
SCHEMBL47893 0.82 SLC6A3 (0.71) SLC6A3KMT2AHTTMAPTHSD17B10
SCHEMBL30373246 0.81 SLC6A3 (1.00) SLC6A3KMT2AHTTMAPTHSD17B10
SCHEMBL2284514 0.81 SLC6A3 (1.00) SLC6A3KMT2AHTTMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed