SCHEMBL2284514

SCHEMBL2284514

COC(=O)c1ccccc1OC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 1.00
MAPT P10636 3/20 0.72
KMT2A Q03164 6/20 0.70
PRSS1 P07477 1/20 0.67
ACR P10323 1/20 0.67
TSHR P16473 2/20 0.62
HTT P42858 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.58
HSD17B10 Q99714 3/20 0.56
LMNA P02545 3/20 0.56
KDM4E B2RXH2 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.54
GAA P10253 2/20 0.52
ALDH1A1 P00352 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
MEN1 O00255 1/20 0.50
JAK2 O60674 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30373246 1.00 SLC6A3 (1.00) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL6813193 0.95 SLC6A3 (0.90) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL5706076 0.93 SLC6A3 (0.87) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL7871178 0.92 SLC6A3 (0.84) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL5706114 0.90 SLC6A3 (0.81) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL7615922 0.88 SLC6A3 (0.79) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL6812283 0.88 SLC6A3 (0.79) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL5706028 0.87 SLC6A3 (0.77) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL5706030 0.87 SLC6A3 (0.77) SLC6A3MAPTKMT2APRSS1ACR
SCHEMBL1058373 0.87 SLC6A3 (0.77) SLC6A3MAPTKMT2APRSS1ACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1257920-C Catalyst component for olefinic polymerization and its catalyst CHINA PETROLEUM & CHEMICAL (CN) 2006-05-31 CN claimed
CN-1611515-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CO LTD (CN) 2005-05-04 CN claimed
EP-0250210-B1 METHOD OF FABRICATING METAL-CERAMIC COMPOSITES, AND METAL-CERAMIC COMPOSITES MADE THEREBY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-04-22 EP claimed
EP-2365957-B1 METHOD FOR MAKING CARBONATES AND ESTERS SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-22 EP disclosed
US-9351980-B2 Di-aspirin derivatives THE UNIVERSITY OF WOLVERHAMPTON (GB) 2016-05-31 US disclosed
US-9351980-B2 Di-aspirin derivatives THE UNIVERSITY OF WOLVERHAMPTON (GB) 2016-05-31 US disclosed
WO-2014122664-A1 LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-08-14 WO disclosed
US-20130035317-A1 Di-Aspirin Derivatives THE UNIVERISTY OF WOLVERHAMPTON (GB) 2013-02-07 US disclosed
US-20130035317-A1 Di-Aspirin Derivatives THE UNIVERISTY OF WOLVERHAMPTON (GB) 2013-02-07 US disclosed
EP-2365957-A2 METHOD FOR MAKING CARBONATES AND ESTERS SABIC Innovative Plastics IP B.V. (NL) 2011-09-21 EP disclosed
WO-2011098839-A2 DI-ASPIRIN DERIVATIVES THE UNIVERSITY OF WOLVERHAMPTON (GB) 2011-08-18 WO disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
CN-1380896-A Aromatic polycarbonate composition, process for producing the same, and molded article thereof TEIJIN LTD (JP) 2002-11-20 CN disclosed
CN-1351632-A Aromatic polycarbonate composition TEIJIN LTD (JP) 2002-05-29 CN disclosed
US-6323302-B1 SUPPLYING AROMATIC DIHYDROXY COMPOUND POWDER AND A CARBONIC ACID DIESTER INTO MELTING VESSEL THROUGH A TRANSPORTATION PIPING; MIXING MELTING; INITIATING MELT POLYMERIZATION IN PRESENCE OR ABSENCE OF CATALYST TEIJIN LIMITED (JP) 2001-11-27 US disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
CN-1252817-A Process for producing polycarbonate resin TEIJIN LTD (JP) 2000-05-10 CN disclosed
EP-0992522-A1 CARBONIC DIESTER, AROMATIC POLYCARBONATE, PRODUCTION APPARATUS, AND PROCESS FOR PRODUCTION TEIJIN LIMITED (JP) 2000-04-12 EP disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035317-A1 Di-Aspirin Derivatives SDHA, DLD, DPYD SLC6A3 2921/4885MAPT 4504/4885KMT2A 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.