Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123036 | 0.92 | MAOB (0.64) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL31025721 | 0.87 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL340620 | 0.87 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL9236564 | 0.87 | SMPD1 (0.73) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL12526571 | 0.87 | SMPD1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL8231047 | 0.85 | MEN1 (0.69) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL7987656 | 0.85 | LTB4R (0.66) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL7994027 | 0.85 | LTB4R (0.66) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL1602208 | 0.84 | MRGPRX4 (0.53) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 | |
| SCHEMBL11179076 | 0.82 | MAOB (0.56) | NPC1RAB9ASMN1; SMN2HPGDSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |